Osteoinductivity of Demineralized Bone Matrix Is Independent of Donor Bisphosphonate Use
نویسندگان
چکیده
منابع مشابه
Comparative evaluation of the osteoinductivity of two formulations of human demineralized bone matrix.
In the United States, demineralized bone matrix (DBM) is considered a transplantable tissue and therefore is regulated primarily by the American Association of Tissue Banks. Even though DBM is not subjected to the same regulations relative to performance claims as medical devices are, one would expect different processing methods might yield DBM preparations of different osteoinductive potentia...
متن کاملThe effect of thrombin activation of platelet-rich plasma on demineralized bone matrix osteoinductivity.
BACKGROUND Demineralized bone matrix is an osteoinductive and osteoconductive material that is often used in orthopaedic surgery to induce bone formation. Autologous platelet-rich plasma, which contains proliferative and chemoattractant growth factors, has been used as a demineralized bone matrix adjuvant with mixed results. One variable during clinical use appears to be whether the platelet-ri...
متن کاملThe Effect of Poloxamer 407-Based Hydrogel on the Osteoinductivity of Demineralized Bone Matrix
BACKGROUND Demineralized bone matrix (DBM) is used for bone healing due to its osteoinductivity, but it requires a carrier for clinical application. Here, we report the effects on the osteoinductivity of DBM by use of a poloxamer 407-based hydrogel as the carrier, compared to sterile water. METHODS DBM-W and DBM-H represent 27 wt% of DBM with sterile water and DBM with a poloxamer 407-based h...
متن کاملThe effect of gamma irradiation on the osteoinductivity of demineralized human bone allograft.
The gamma irradiation has been used for end sterilization of allograft bones and its effects with a 25 kGy dosage on the osteoinductive properties of demineralized bone allograft powder was studied. This work carried out using an experimental method in an animal model. In this study the demineralized bone allograft powder which had been sterilized and prepared with gamma irradiation in a 25 kGy...
متن کاملDemineralized bone matrix and spinal arthrodesis.
Spinal fusion is a gold-standard treatment for many disorders of the spine with autogenous bone graft as the gold-standard source for augmenting fusion. However, the morbidity and limitations of autogenous bone grafting has motivated the search for bone graft alternatives. One such alternative is demineralized bone matrix (DBM). The purpose of this paper is to describe and characterize the prop...
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ژورنال
عنوان ژورنال: The Journal of Bone and Joint Surgery-American Volume
سال: 2011
ISSN: 0021-9355
DOI: 10.2106/jbjs.j.01469